I am on 1500 mg of Metformin per day, plus 750 mg of Tricor for the metabolic syndrome. These are both considered "toxic" on the safefetus.com website. My question is, how am I supposed to remain healthy by taking my pills, but TTC at the same time? Also, if I do become pregnant and don't know it, won't it have an effect on the baby? And, how do you regulate the PCOS if you can't take your meds while being pregnant?
And another thing, it says these drugs can transfer into breast milk, so are you not supposed to breastfeed??

I was on met for the first trimester. Studies have shown that met can actually reduce a woman with PCOS miscarriage risk. Without met the risk can be as high as 60% and with met it drops to 10%. Met can actually help you ovulate and is perfectly safe to take while TTC, while pregnant and even while breastfeeding. I stopped my met at 13 weeks and went back on once I had the baby. If you are taking met for type 2 diabetes they will keep you on it for the duration of your pregnancy more then likely.

I dunno anything about the other med tho

Metformin is a B class drug. Tylenol, which doctors tell you are safe, is a B class drug. I continued to take my metformin, but in a reduced amount. I was on 2000 mg, I currently take 1000mg a day. My OB said it won't hurt, but won't really help. Well, I disagree. I went off of it for two weeks, and failed my early glucose test. Went back on it and have since passed a 3 hour one and the 28 week one hour glucose test. Coincidence, it is possible, but I truly believe that my body NEEDS metformin now after a few years of being on it, to properly regulate insulin. I have researched it, and I think it is the best decision for ME. I haven't read of any bad things happening to babies that mothers stayed on the met. I HAVE heard of bad things happening (miscarriage increases in the first tri, GD, pre eclampsia, etc) when they come off of it. My OB said the main reason she suggests getting off of it is that if you should be transferred to a high risk OB, they don't like you to be on it, because your chance of C section is higher, and you should be off of Met for 48 hours before any surgery. I am going to stop taking it when I think I am getting close to giving birth, just in case.


Many fertility specialists suggest you stay on it for the first trimester.
Do I believe it is POSSIBLE for it to have ill effects on the fetus/baby, absolutely it is. But I made my choice and I feel good about it.

The other drug, I have never heard of. If you want to go off of them both, you just need to follow the BEST low glycemic, healthy diet you can....which women with PCOS should do anyway.

Now, with breastfeeding, I may reconsider taking it. I think it passes more easily through breastmilk than to the fetus while in the womb. I haven't decided on that yet, and will obviously depend on whether I am successful at breast feeding. If I were you, I would just research it more. I would think that most would say to not use it, if I had to guess.


Nonetheless, good luck with your TTC and decisions!

oops, double post

I was on met for the first trimester. Studies have shown that met can actually reduce a woman with PCOS miscarriage risk. Without met the risk can be as high as 60% and with met it drops to 10%. Met can actually help you ovulate and is perfectly safe to take while TTC, while pregnant and even while breastfeeding. I stopped my met at 13 weeks and went back on once I had the baby. If you are taking met for type 2 diabetes they will keep you on it for the duration of your pregnancy more then likely.

I dunno anything about the other med tho
Thank you so much!!


Metformin is a B class drug. Tylenol, which doctors tell you are safe, is a B class drug. I continued to take my metformin, but in a reduced amount. I was on 2000 mg, I currently take 1000mg a day. My OB said it won't hurt, but won't really help. Well, I disagree. I went off of it for two weeks, and failed my early glucose test. Went back on it and have since passed a 3 hour one and the 28 week one hour glucose test. Coincidence, it is possible, but I truly believe that my body NEEDS metformin now after a few years of being on it, to properly regulate insulin. I have researched it, and I think it is the best decision for ME. I haven't read of any bad things happening to babies that mothers stayed on the met. I HAVE heard of bad things happening (miscarriage increases in the first tri, GD, pre eclampsia, etc) when they come off of it. My OB said the main reason she suggests getting off of it is that if you should be transferred to a high risk OB, they don't like you to be on it, because your chance of C section is higher, and you should be off of Met for 48 hours before any surgery. I am going to stop taking it when I think I am getting close to giving birth, just in case.


Many fertility specialists suggest you stay on it for the first trimester.
Do I believe it is POSSIBLE for it to have ill effects on the fetus/baby, absolutely it is. But I made my choice and I feel good about it.

The other drug, I have never heard of. If you want to go off of them both, you just need to follow the BEST low glycemic, healthy diet you can....which women with PCOS should do anyway.

Now, with breastfeeding, I may reconsider taking it. I think it passes more easily through breastmilk than to the fetus while in the womb. I haven't decided on that yet, and will obviously depend on whether I am successful at breast feeding. If I were you, I would just research it more. I would think that most would say to not use it, if I had to guess.


Nonetheless, good luck with your TTC and decisions!
That is really informative, and I appreciate it greatly! Why is the c section rate higher?
It is frustrating because I (L) my endocrinologist, but he never directly answers my questions :confused

I take both Metformin and Tricor, everyone has given you wonderful info on metformin so I don't need to go there. The Tricor is for high cholsterol and high triglyceride levels. thats what it treats. I take mine for my high triglycerides. This is a category C drug so this medication may be harmful to an unborn baby and it shouldn't be used by nursing mothers either.

I am on 1500 mg of Metformin per day, plus 750 mg of Tricor for the metabolic syndrome. These are both considered "toxic" on the safefetus.com website. My question is, how am I supposed to remain healthy by taking my pills, but TTC at the same time? Also, if I do become pregnant and don't know it, won't it have an effect on the baby? And, how do you regulate the PCOS if you can't take your meds while being pregnant?
And another thing, it says these drugs can transfer into breast milk, so are you not supposed to breastfeed??

My friend has PCOS and she just gave birth to a beautiful, healthy (and totally lovable) little boy in November. they took her off the Metformin while she was pregnant. I don't know about breastfeeding because she was unable to, her body just didn't produce milk :dunno
Doesn't pregnancy kind of control PCOS?
I would call a 24 hour Walgreens and talk to a pharmacist. I trust them a lot more when it comes to drugs than doctors.

With my daughter my fertility specliast kept me on 1500mg of Met for the first trimester.
For this pregnancy my dr kept me on it till 12wks (I stayed on till last week though for my peace of mind).
My daughter is healthy and perfectly fine. I know sooo many women who stayed on Met their entire pregnancy and there was no problem with their children.

The c-section rate is higher, usually, when you are referred to a high risk OB. Usually, it is because of whatever reason you are referred there. That is what I meant. Sorry if I was unclear.

I take both Metformin and Tricor, everyone has given you wonderful info on metformin so I don't need to go there. The Tricor is for high cholsterol and high triglyceride levels. thats what it treats. I take mine for my high triglycerides. This is a category C drug so this medication may be harmful to an unborn baby and it shouldn't be used by nursing mothers either.
Do you have any idea what they would do to control my cholesterol levels if I was pregnant and couldn't take the Tricor? The high cholesterol is from metabolic syndrome, so maybe that would go away during pregnancy? :confused

My friend has PCOS and she just gave birth to a beautiful, healthy (and totally lovable) little boy in November. they took her off the Metformin while she was pregnant. I don't know about breastfeeding because she was unable to, her body just didn't produce milk :dunno
Doesn't pregnancy kind of control PCOS?
I would call a 24 hour Walgreens and talk to a pharmacist. I trust them a lot more when it comes to drugs than doctors.
That's a really good question

The c-section rate is higher, usually, when you are referred to a high risk OB. Usually, it is because of whatever reason you are referred there. That is what I meant. Sorry if I was unclear.
Is the c-section rate higher for women with PCOS in general?

Pregnancy can help the hormone issues of PCOS. I couldnt breastfeed my son soley because my milk never fully came in. That can also be a side effect of PCOS. My LC and I researched what was wrong with my supply and found that

Pregnancy can help the hormone issues of PCOS. I couldnt breastfeed my son soley because my milk never fully came in. That can also be a side effect of PCOS. My LC and I researched what was wrong with my supply and found that

I am really sorry that you went through that :bigsadhug
At least I know what to expect though, so thank you for sharing that with me :hugs